Integration of physiological factors into a mathematical  model of the human eye condition

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Vladimir V. Vychuzhanin
Alexey V. Vychuzhanin
Olga V. Guzun
Oleg S. Zadorozhny

Abstract

Mathematical models of the human eye serve as adaptive tools for analyzing and predicting ophthalmological parameters, considering their interrelations and individual patient characteristics. Their application in ophthalmology enhances the quality of diagnostics, monitoring, and treatment, ultimately improving patients' quality of life. The developed eye condition model is based on a mathematical function that integrates physiological eye parameters, each assigned a weight coefficient to determine its impact on the overall condition index. The model accounts for complex nonlinear interactions between parameters, allowing for a more accurate representation of physiological processes. To optimize the weight coefficients, the L-BFGS-B method is employed—an iterative algorithm that efficiently minimizes the loss function and ensures high accuracy in adapting the model to individual patient data.This model offers several advantages: it enables early diagnosis of diseases such as glaucoma, cataracts, and macular degeneration, tailors treatment plans based on individual patient parameters, and facilitates disease monitoring and progression prediction for timely therapy adjustments. Furthermore, the model can be integrated with modern technologies, including virtual and augmented reality systems, as well as artificial intelligence for automated diagnostics. Thus, the proposed mathematical model serves as a universal tool for analyzing eye conditions and developing innovative diagnostic and therapeutic technologies. By incorporating parameter interdependencies and their effects on the physiological state of the eye, it provides ophthalmologists with a powerful instrument for enhancing diagnostics, prediction, and disease monitoring in vision healthcare.

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Systems analysis, applied information systems and technologies

Authors

Author Biographies

Vladimir V. Vychuzhanin, Odesa Polytechnic National University, 1, Shevchenko Ave. Odesa, 65044, Ukraine

Doctor of Engineering Sciences, Professor, Head of Department of Information Technology

Scopus Author ID: 57193025809

Alexey V. Vychuzhanin, Odesa Polytechnic National University, 1, Shevchenko Ave. Odesa, 65044, Ukraine

PhD, Assistant of Department of Computer Systems and Software Technologies

Scopus Author ID: 57223830519

Olga V. Guzun, Filatov Institute of Eye Diseases and Tissue Therapy of the National Academy of Medical Sciences of Ukraine, 49/51, Frantsuzsky Boulevard. Odesa, 65044, Ukraine

Candidate of Medical Sciences

Scopus Author ID: 57194162945

Oleg S. Zadorozhny, Filatov Institute of Eye Diseases and Tissue Therapy of National Academy of Medical Sciences of Ukraine, 49/51, Frantsuzsky Boulevard. Odesa, 65044, Ukraine

Doctor of Medical Sciences

Scopus Author ID: 28667545400

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